UQCRH

Across TCGA patient cohorts, UQCRH mutation is significantly associated with the RNA expression of many other genes, with 96 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible UQCRH-associated genes across cancer lineages are LNCPRESS2, NIPA2P3, and RNU6-56P. Each is linked with UQCRH in more than 2 cancer types. Because this analysis shows association rather than direction, both UQCRH-to-partner and partner-to-UQCRH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LNCPRESS2 grouped by UQCRH-low versus UQCRH-high in PRAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UQCRH→partner) and Y-score (partner→UQCRH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PRAD	LNCPRESS2 →	+0.164	+7.939	<.001	.008	3	3
UCEC	NIPA2P3 →	+0.107	+5.582	.003	.002	3	2
PRAD	RNU6-56P →	+0.438	+7.939	<.001	.008	3	2
COAD	MBD3L3 →	+0.129	+7.741	<.001	.009	3	2
UCEC	MIR652 →	+0.684	+5.123	<.001	.004	3	2
UCEC	BCAS2P3 →	+0.229	+5.335	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 96 associations by consensus.

LNCPRESS2 by UQCRH expression — PRAD

Explore this box plot interactively →