UQCRH

Across TCGA pan-cancer cohorts, UQCRH RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated UQCRH data layer compared with 1 for mutation status and 3 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher UQCRH RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated UQCRH expression acts as an unfavorable survival marker, although some lineages such as STAD and KIRC show a favorable association.

ACC, KICH, and LIHC are the cancer types where UQCRH RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.140	0.675	<.001	95	view →
KICH	DFS	Median	III,IV	0.292	0.905	<.001	86	view →
LIHC	OS	Median	All	0.685	0.864	<.001	72	view →
SARC	DFS	Median	All	0.508	0.709	<.001	39	view →
SCLC	DFS	Tertile	II,III,IV	0.388	0.734	.002	34	view →
SKCM	DFS	Median	III,IV	0.492	0.786	.002	19	view →
LUAD	OS	Quartile	III,IV	0.340	0.712	.007	19	view →
PRAD	DFS	Median	All	0.696	0.870	<.001	18	view →
STAD	DFS	Median	II,III,IV	0.597	0.431	.009	17	view →
BRCA	OS	Quartile	III,IV	0.768	0.924	.002	17	view →
KIRC	OS	Median	All	0.754	0.577	.001	16	view →
READ	DFS	Tertile	II,III,IV	0.940	0.567	.003	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

UQCRH–ACC (DFS)

Open the ACC breakdown →