UQCRH

Across TCGA pan-cancer cohorts, UQCRH RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of UQCRH’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where UQCRH RNA is more highly expressed in tumor relative to normal tissue. In most cancer types UQCRH is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

LUAD, LIHC, and LUSC are the cancer types where UQCRH tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in UQCRH RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	All	+0.796	<.001	11	view →
LIHC	Female	II,III,IV	+1.484	<.001	9	view →
LUSC	Female	All	+1.439	<.001	8	view →
KIRC	Male	II,III,IV	−1.395	<.001	8	view →
BLCA	Male	All	+0.891	<.001	7	view →
STAD	All	II,III,IV	+0.388	.002	6	view →
CHOL	All	All	+2.374	<.001	5	view →
HNSC	All	All	+0.199	.013	5	view →
KICH	All	All	−0.684	<.001	4	view →
BRCA	All	II,III,IV	+0.201	.005	4	view →
KIRP	Male	All	−0.532	.046	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

UQCRH–LUAD

Open the LUAD breakdown →