UQCRH

Across TCGA cell cohorts, UQCRH RNA expression is significantly associated with the go_rna of many other GO terms, with 4,644 significant associations in total. BONE shows the largest number of these associations.

The most reproducible UQCRH-associated GO terms across cancer lineages are Mitochondrial gene expression, Regulation of hydrolase activity, and Mitochondrial RNA catabolic process. Each is linked with UQCRH in more than 13 cancer types. Because this analysis shows association rather than direction, both UQCRH-to-partner and partner-to-UQCRH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial gene expression grouped by UQCRH-low versus UQCRH-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UQCRH→partner) and Y-score (partner→UQCRH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Mitochondrial gene expression →	+0.153	+0.892	<.001	<.001	3	14
BONE	Regulation of hydrolase activity →	-0.075	-0.942	<.001	<.001	3	12
BONE	Mitochondrial RNA catabolic process →	+0.158	+0.768	<.001	.007	3	12
UPPER_AERODIGESTIVE_TRACT	Transcription initiation at mitochondrial promoter →	+0.109	+0.997	.004	.004	3	12
BONE	Mitochondrial RNA metabolic process →	+0.079	+0.614	<.001	<.001	3	11
BONE	tRNA threonylcarbamoyladenosine modification →	+0.117	+0.655	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,644 associations by consensus.

Mitochondrial gene expression by UQCRH expression — BONE

Explore this box plot interactively →