UQCRFS1

Across TCGA patient cohorts, UQCRFS1 mutation is significantly associated with the RNA expression of many other genes, with 179 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible UQCRFS1-associated genes across cancer lineages are RN7SL483P, RN7SKP22, and RNA5SP86. Each is linked with UQCRFS1 in more than 2 cancer types. Because this analysis shows association rather than direction, both UQCRFS1-to-partner and partner-to-UQCRFS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL483P grouped by UQCRFS1-low versus UQCRFS1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UQCRFS1→partner) and Y-score (partner→UQCRFS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RN7SL483P →	+0.204	+5.497	<.001	.004	3	3
HNSC	RN7SKP22 →	+0.212	+4.372	.006	.007	3	2
COAD	RNA5SP86 →	+1.468	+6.142	<.001	<.001	3	2
HNSC	AFF2-IT1 →	+0.164	+4.822	<.001	.006	3	2
COAD	RAD51AP1P1 →	+0.966	+4.577	<.001	.004	3	2
COAD	RN7SL687P →	+0.578	+4.516	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 179 associations by consensus.

RN7SL483P by UQCRFS1 expression — BLCA

Explore this box plot interactively →