Q-omics provides the consensus-scored RN7SKP22 profile across patient tissues and cancer cell-line models. RN7SKP22 expression is associated with patient survival in 17 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, RN7SKP22 is differentially expressed in 7, with the highest sampling consensus in KIRC. Additionally, RN7SKP22 RNA expression shows 7,350 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight ACC, KIRC, and TGCT as cancer lineages where RN7SKP22 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RN7SKP22 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RN7SKP22 survival associations across molecular data types. RN7SKP22 RNA expression shows survival associations in the most cancer types (17). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RN7SKP22 RNA expression–survival associations across cancer types. High RN7SKP22 expression shows unfavorable associations in ACC, DLBC, THCA, SKCM and KIRC, but favorable associations in BLCA. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for RN7SKP22 RNA expression.
This table summarizes RN7SKP22 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 7. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for RN7SKP22. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RN7SKP22 shows lower tumor expression in KICH, KIRP and THCA and higher tumor expression in KIRC, HNSC and LIHC. The KIRC box plot shows higher RN7SKP22 RNA expression in tumor versus normal tissue (log2 FC = +0.144, t-test p = .003).
This table shows molecular features associated with RN7SKP22 in patient tissues and cancer cell lines. In patient samples, RN7SKP22 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
