UQCRB

Across TCGA patient cohorts, UQCRB protein abundance is significantly associated with the protein abundance of many other proteins, with 22,662 significant associations in total. GBM shows the largest number of these associations.

The most reproducible UQCRB-associated proteins across cancer lineages are UQCRC1, UQCRC2, and UQCRFS1. Each is linked with UQCRB in more than 9 cancer types. Because this analysis shows association rather than direction, both UQCRB-to-partner and partner-to-UQCRB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UQCRB versus UQCRC1 in UCEC, with a Pearson correlation of 0.88.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (UQCRB→partner) and Y-score (partner→UQCRB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	UQCRC1 →	+0.600	+0.624	<.001	<.001	3	10
UCEC	UQCRC2 →	+0.561	+0.624	<.001	<.001	3	10
OV	UQCRFS1 →	+0.505	+0.683	<.001	<.001	3	10
UCEC	UQCRQ →	+0.710	+0.608	<.001	<.001	3	10
COAD	PTCD3 →	+0.337	+0.385	<.001	<.001	3	10
COAD	SDHB →	+0.467	+0.467	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,662 associations by consensus.

UQCRB vs UQCRC1 — UCEC

Explore this scatter interactively →