UPK1B

Across TCGA cell cohorts, UPK1B RNA expression is significantly associated with the go_rna of many other GO terms, with 1,974 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible UPK1B-associated GO terms across cancer lineages are Negative regulation of transforming growth factor beta production, Regulation of inclusion body assembly, and Protein stabilization. Each is linked with UPK1B in more than 6 cancer types. Because this analysis shows association rather than direction, both UPK1B-to-partner and partner-to-UPK1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of transforming growth factor beta production grouped by UPK1B-low versus UPK1B-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UPK1B→partner) and Y-score (partner→UPK1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of transforming growth factor beta production →	+0.250	+3.625	.001	.001	3	7
URINARY_TRACT	Regulation of inclusion body assembly →	+0.100	+3.957	<.001	.001	3	7
STOMACH	Protein stabilization →	+0.046	+1.701	.001	.009	3	7
OESOPHAGUS	Positive regulation of protein import into nucleus →	+0.097	+3.435	.004	.006	2	7
URINARY_TRACT	Cell-substrate junction organization →	+0.149	+4.467	<.001	<.001	3	6
URINARY_TRACT	Cell-substrate junction assembly →	+0.152	+4.467	<.001	<.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,974 associations by consensus.

Negative regulation of transforming growth factor beta production by UPK1B expression — OESOPHAGUS

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