UPK1B

Across TCGA cell cohorts, UPK1B mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UPK1B-associated genes across cancer lineages are FAM205A and GSG1L2. Each is linked with UPK1B in more than 1 cancer types. Because this analysis shows association rather than direction, both UPK1B-to-partner and partner-to-UPK1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM205A grouped by UPK1B-low versus UPK1B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UPK1B→partner) and Y-score (partner→UPK1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FAM205A →	+0.019	+3.766	.001	.004	3	1
LARGE_INTESTINE	GSG1L2 →	+0.013	+4.022	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

FAM205A by UPK1B expression — LARGE_INTESTINE

Explore this box plot interactively →