UNC5C

Across TCGA cell cohorts, UNC5C RNA expression is significantly associated with the go_rna of many other GO terms, with 1,841 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible UNC5C-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Electron transport chain, and Proton motive force-driven ATP synthesis. Each is linked with UNC5C in more than 6 cancer types. Because this analysis shows association rather than direction, both UNC5C-to-partner and partner-to-UNC5C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by UNC5C-low versus UNC5C-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UNC5C→partner) and Y-score (partner→UNC5C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Negative regulation of syncytium formation by plasma membrane fusion →	+0.094	+0.307	<.001	.008	3	7
SKIN	Electron transport chain →	+0.085	+0.891	<.001	<.001	3	7
SKIN	Proton motive force-driven ATP synthesis →	+0.101	+0.733	<.001	<.001	3	6
SKIN	Proton motive force-driven mitochondrial ATP synthesis →	+0.101	+0.881	<.001	<.001	3	6
SOFT_TISSUE	Cellular response to rapamycin →	+0.063	+1.454	.002	.004	2	7
SKIN	Aerobic electron transport chain →	+0.094	+0.744	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,841 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by UNC5C expression — BLOOD_Lymphoma

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