UNC13A

Across TCGA patient cohorts, UNC13A RNA expression is significantly associated with the protein abundance of many other proteins, with 10,847 significant associations in total. GBM shows the largest number of these associations.

The most reproducible UNC13A-associated proteins across cancer lineages are AP3B2_S272, RPN1, and RPN2. Each is linked with UNC13A in more than 4 cancer types. Because this analysis shows association rather than direction, both UNC13A-to-partner and partner-to-UNC13A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UNC13A versus AP3B2_S272 in BRCA, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (UNC13A→partner) and Y-score (partner→UNC13A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	AP3B2_S272 →	+1.406	+1.264	.008	.003	3	5
PDAC	RPN1 →	-0.346	-0.505	.001	<.001	3	3
GBM	RPN2 →	-0.275	-1.321	.002	<.001	3	3
BRCA	SLC8A2_S622 →	+1.647	+3.242	.005	.006	3	3
LSCC	SMARCAD1_T71 →	+1.021	+1.083	<.001	<.001	3	3
BRCA	SNAP25 →	+1.233	+2.606	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,847 associations by consensus.

UNC13A vs AP3B2_S272 — BRCA

Explore this scatter interactively →