UNC13A

Across TCGA cell cohorts, UNC13A RNA expression is significantly associated with the go_rna of many other GO terms, with 1,891 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible UNC13A-associated GO terms across cancer lineages are Aldosterone biosynthetic process, Nonassociative learning, and Hindbrain radial glia guided cell migration. Each is linked with UNC13A in more than 6 cancer types. Because this analysis shows association rather than direction, both UNC13A-to-partner and partner-to-UNC13A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aldosterone biosynthetic process grouped by UNC13A-low versus UNC13A-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UNC13A→partner) and Y-score (partner→UNC13A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Aldosterone biosynthetic process →	+1.639	+2.737	<.001	<.001	3	7
SOFT_TISSUE	Nonassociative learning →	+1.185	+2.875	<.001	<.001	3	7
STOMACH	Hindbrain radial glia guided cell migration →	-0.207	-2.079	<.001	.003	3	6
SOFT_TISSUE	Adult locomotory behavior →	+0.127	+2.831	<.001	<.001	3	6
LUNG_SCLC	Negative regulation of glucagon secretion →	+1.477	+2.550	<.001	<.001	3	6
BLOOD_Lymphoma	ATP synthesis coupled electron transport →	+0.054	+0.157	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,891 associations by consensus.

Aldosterone biosynthetic process by UNC13A expression — SOFT_TISSUE

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