UNC119B

Across TCGA patient cohorts, UNC119B protein abundance is significantly associated with the protein abundance of many other proteins, with 20,378 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible UNC119B-associated proteins across cancer lineages are PTPRC_S994, PTPRJ, and ARL3. Each is linked with UNC119B in more than 6 cancer types. Because this analysis shows association rather than direction, both UNC119B-to-partner and partner-to-UNC119B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UNC119B versus PTPRC_S994 in PDAC, with a Pearson correlation of -0.52.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (UNC119B→partner) and Y-score (partner→UNC119B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PTPRC_S994 →	-0.748	-0.385	<.001	<.001	3	7
PDAC	PTPRJ →	-0.381	-0.331	<.001	<.001	3	7
COAD	ARL3 →	+0.381	+0.353	<.001	<.001	3	6
PDAC	CYBA_T147 →	-1.484	-0.589	<.001	<.001	3	6
UCEC	CYBB →	-0.770	-0.238	<.001	<.001	3	6
CCRCC	FCER1G →	-0.956	-0.297	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,378 associations by consensus.

UNC119B vs PTPRC_S994 — PDAC

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