UNC119B

Across TCGA patient cohorts, UNC119B mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UNC119B-associated genes across cancer lineages are Ku80, VHL, and MEK1. Each is linked with UNC119B in more than 1 cancer types. Because this analysis shows association rather than direction, both UNC119B-to-partner and partner-to-UNC119B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by UNC119B-low versus UNC119B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UNC119B→partner) and Y-score (partner→UNC119B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.314	+3.009	.011	.019	3	1
UCEC	VHL →	-0.992	-3.321	.005	.010	3	1
UCEC	MEK1 →	+0.527	+3.000	.005	.036	2	1
UCEC	SLC1A5 →	-0.442	-3.314	.047	.010	2	1
UCEC	INPP4B →	-0.415	-3.308	.014	.010	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Ku80 by UNC119B expression — UCEC

Explore this box plot interactively →