UMODL1

Across TCGA cell cohorts, UMODL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,191 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UMODL1-associated GO terms across cancer lineages are Regulation of G1/S transition of mitotic cell cycle, Negative regulation of syncytium formation by plasma membrane fusion, and Regulation of proteasomal protein catabolic process. Each is linked with UMODL1 in more than 8 cancer types. Because this analysis shows association rather than direction, both UMODL1-to-partner and partner-to-UMODL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of G1/S transition of mitotic cell cycle grouped by UMODL1-low versus UMODL1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UMODL1→partner) and Y-score (partner→UMODL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of G1/S transition of mitotic cell cycle →	+0.044	+1.190	.001	.005	3	9
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.143	+0.066	<.001	.003	3	9
OESOPHAGUS	Regulation of proteasomal protein catabolic process →	+0.085	+0.087	<.001	.001	3	8
OESOPHAGUS	Cellular respiration →	+0.116	+0.096	.002	.001	3	8
OESOPHAGUS	Circadian rhythm →	+0.057	+0.073	<.001	.002	3	7
BLOOD_Leukemia	Regulation of cell cycle G1/S phase transition →	+0.044	+0.709	<.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,191 associations by consensus.

Regulation of G1/S transition of mitotic cell cycle by UMODL1 expression — BLOOD_Lymphoma

Explore this box plot interactively →