UMOD

Across TCGA patient cohorts, UMOD RNA expression is significantly associated with the go_rna of many other GO terms, with 6,451 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UMOD-associated GO terms across cancer lineages are Endothelial cell activation, Midbody abscission, and Metanephric loop of Henle development. Each is linked with UMOD in more than 7 cancer types. Because this analysis shows association rather than direction, both UMOD-to-partner and partner-to-UMOD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endothelial cell activation grouped by UMOD-low versus UMOD-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UMOD→partner) and Y-score (partner→UMOD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Endothelial cell activation →	+0.081	+0.129	<.001	<.001	3	8
STAD	Midbody abscission →	+0.051	+0.107	<.001	<.001	3	7
KICH	Metanephric loop of Henle development →	-0.079	-0.913	<.001	<.001	3	7
KICH	Metanephric distal tubule development →	-0.093	-0.898	<.001	<.001	2	8
KIRP	Response to water deprivation →	-0.089	-0.679	<.001	<.001	3	6
STAD	tRNA 5'-end processing →	+0.070	+0.109	<.001	.003	1	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,451 associations by consensus.

Endothelial cell activation by UMOD expression — STAD

Explore this box plot interactively →