ULBP2

Across TCGA patient cohorts, ULBP2 mutation is significantly associated with the RNA expression of many other genes, with 648 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ULBP2-associated genes across cancer lineages are HTATSF1P1, RNU6-1137P, and RNA5SP232. Each is linked with ULBP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ULBP2-to-partner and partner-to-ULBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HTATSF1P1 grouped by ULBP2-low versus ULBP2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ULBP2→partner) and Y-score (partner→ULBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	HTATSF1P1 →	+0.062	+4.893	<.001	.005	3	2
COAD	RNU6-1137P →	+0.467	+5.392	<.001	.002	3	2
BRCA	RNA5SP232 →	+0.259	+8.055	.004	.007	3	2
BRCA	RBMY2AP →	+0.029	+8.055	<.001	.007	3	2
UCEC	RN7SL248P →	+0.092	+3.847	<.001	.001	3	2
UCEC	ATP2B2-IT1 →	+0.049	+3.707	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 648 associations by consensus.

HTATSF1P1 by ULBP2 expression — COAD

Explore this box plot interactively →