UGT2B4

Across TCGA cell cohorts, UGT2B4 RNA expression is significantly associated with the go_rna of many other GO terms, with 803 significant associations in total. LIVER shows the largest number of these associations.

The most reproducible UGT2B4-associated GO terms across cancer lineages are Protein exit from endoplasmic reticulum, Maintenance of blood vessel diameter homeostasis by renin-angiotensin, and Actin filament depolymerization. Each is linked with UGT2B4 in more than 2 cancer types. Because this analysis shows association rather than direction, both UGT2B4-to-partner and partner-to-UGT2B4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein exit from endoplasmic reticulum grouped by UGT2B4-low versus UGT2B4-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UGT2B4→partner) and Y-score (partner→UGT2B4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Protein exit from endoplasmic reticulum →	+0.117	+3.410	.001	.008	3	3
LIVER	Maintenance of blood vessel diameter homeostasis by renin-angiotensin →	+1.841	+3.103	<.001	.001	3	3
LIVER	Actin filament depolymerization →	-0.139	-2.710	.004	.006	3	3
LIVER	Intracellular sterol transport →	+0.070	+4.559	<.001	.001	3	3
LIVER	Monocarboxylic acid catabolic process →	+0.074	+3.739	<.001	<.001	3	3
BLOOD_Myeloma	Positive regulation of natural killer cell cytokine production →	-0.273	-0.032	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 803 associations by consensus.

Protein exit from endoplasmic reticulum by UGT2B4 expression — LIVER

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