UEVLD

Across TCGA patient cohorts, UEVLD mutation is significantly associated with the RNA expression of many other genes, with 830 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UEVLD-associated genes across cancer lineages are RNU6-389P, ARPC1BP1, and VPS25P1. Each is linked with UEVLD in more than 2 cancer types. Because this analysis shows association rather than direction, both UEVLD-to-partner and partner-to-UEVLD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-389P grouped by UEVLD-low versus UEVLD-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UEVLD→partner) and Y-score (partner→UEVLD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-389P →	+0.406	+4.017	<.001	.003	3	3
LUAD	ARPC1BP1 →	+0.521	+3.690	<.001	.009	3	2
COAD	VPS25P1 →	+0.198	+4.429	<.001	.001	3	2
UCEC	KIF18B →	+0.697	+2.108	.003	.003	3	2
UCEC	IGHD3-16 →	+0.865	+2.233	.002	<.001	3	2
UCEC	PINCR →	+0.320	+2.600	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 830 associations by consensus.

RNU6-389P by UEVLD expression — COAD

Explore this box plot interactively →