UEVLD

Across TCGA pan-cancer cohorts, UEVLD RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of UEVLD’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where UEVLD RNA is more highly expressed in tumor relative to normal tissue. In most cancer types UEVLD is over-expressed in tumor, although a few such as THCA and COAD show the opposite, repressed pattern.

LIHC, THCA, and HNSC are the cancer types where UEVLD tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in UEVLD RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Male	All	+0.927	<.001	9	view →
THCA	Male	III,IV	−0.685	<.001	9	view →
HNSC	All	All	+0.373	<.001	9	view →
BRCA	All	III,IV	+0.658	<.001	6	view →
CHOL	Female	All	+1.823	<.001	5	view →
COAD	Female	All	−0.642	<.001	5	view →
STAD	All	II,III,IV	+0.420	.013	5	view →
KICH	All	All	−0.548	.003	3	view →
READ	All	All	−0.578	.004	2	view →
UCEC	All	All	−0.402	.046	2	view →
LUAD	All	All	+0.208	.008	2	view →
KIRP	Male	All	−0.316	.017	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

UEVLD–LIHC

Open the LIHC breakdown →