UCP1

Across TCGA cell cohorts, UCP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 249 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible UCP1-associated GO terms across cancer lineages are Regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Proton motive force-driven mitochondrial ATP synthesis. Each is linked with UCP1 in more than 4 cancer types. Because this analysis shows association rather than direction, both UCP1-to-partner and partner-to-UCP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by UCP1-low versus UCP1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UCP1→partner) and Y-score (partner→UCP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of myoblast fusion →	+0.143	+0.148	<.001	.008	3	4
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.158	+0.151	<.001	.007	3	4
STOMACH	Proton motive force-driven mitochondrial ATP synthesis →	+0.137	+0.161	.002	.006	3	4
OVARY	Positive regulation of signal transduction by p53 class mediator →	+0.054	+0.165	.003	.007	3	4
OVARY	Regulation of stem cell population maintenance →	+0.045	+0.174	.001	.004	3	4
OVARY	Cytoplasmic translation →	+0.068	+0.169	<.001	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 249 associations by consensus.

Regulation of myoblast fusion by UCP1 expression — STOMACH

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