UCMA

Across TCGA patient cohorts, UCMA RNA expression is significantly associated with the go_rna of many other GO terms, with 6,692 significant associations in total. STAD shows the largest number of these associations.

The most reproducible UCMA-associated GO terms across cancer lineages are Regulation of post-translational protein modification, Regulation of double-strand break repair via nonhomologous end joining, and Protein stabilization. Each is linked with UCMA in more than 12 cancer types. Because this analysis shows association rather than direction, both UCMA-to-partner and partner-to-UCMA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of post-translational protein modification grouped by UCMA-low versus UCMA-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UCMA→partner) and Y-score (partner→UCMA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of post-translational protein modification →	+0.076	+0.195	<.001	<.001	3	13
STAD	Regulation of double-strand break repair via nonhomologous end joining →	+0.059	+0.195	<.001	<.001	3	13
STAD	Protein stabilization →	+0.074	+0.193	<.001	<.001	3	13
STAD	Regulation of cyclin-dependent protein kinase activity →	+0.065	+0.192	<.001	<.001	3	13
STAD	Positive regulation of mitotic cell cycle →	+0.065	+0.181	<.001	<.001	3	13
STAD	Mitochondrial gene expression →	+0.082	+0.214	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,692 associations by consensus.

Regulation of post-translational protein modification by UCMA expression — STAD

Explore this box plot interactively →