UCMA

Across TCGA cell cohorts, UCMA RNA expression is significantly associated with the go_rna of many other GO terms, with 217 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UCMA-associated GO terms across cancer lineages are Positive regulation of viral genome replication, Negative regulation of receptor recycling, and Regulation of lipid localization. Each is linked with UCMA in more than 2 cancer types. Because this analysis shows association rather than direction, both UCMA-to-partner and partner-to-UCMA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of viral genome replication grouped by UCMA-low versus UCMA-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UCMA→partner) and Y-score (partner→UCMA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Positive regulation of viral genome replication →	+0.121	+0.057	<.001	.005	3	3
BLOOD_Leukemia	Negative regulation of receptor recycling →	+0.074	+0.023	.009	.004	3	3
BLOOD_Myeloma	Regulation of lipid localization →	+0.053	+0.054	.007	.006	3	2
BLOOD_Myeloma	Negative regulation of lipid localization →	+0.061	+0.038	.005	.004	3	2
BLOOD_Myeloma	Alcohol catabolic process →	+0.093	+0.039	.002	.003	3	2
BLOOD_Myeloma	Establishment of skin barrier →	+0.119	+0.049	.005	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 217 associations by consensus.

Positive regulation of viral genome replication by UCMA expression — BLOOD_Myeloma

Explore this box plot interactively →