UBXN1

Across TCGA cell cohorts, UBXN1 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UBXN1-associated genes across cancer lineages are KRTAP10-10, PATE4, and DEFA3. Each is linked with UBXN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBXN1-to-partner and partner-to-UBXN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP10-10 grouped by UBXN1-low versus UBXN1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBXN1→partner) and Y-score (partner→UBXN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	KRTAP10-10 →	+0.049	+5.662	<.001	.002	3	1
LARGE_INTESTINE	PATE4 →	+0.046	+4.095	<.001	.009	3	1
LARGE_INTESTINE	DEFA3 →	+0.076	+4.415	<.001	.007	3	1
BLOOD_Leukemia	P2RX3 →	+0.047	+3.551	.001	.008	3	1
BLOOD_Leukemia	CCKAR →	+0.030	+3.824	<.001	.001	3	1
BLOOD_Leukemia	OR5B12 →	+0.031	+3.926	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

KRTAP10-10 by UBXN1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →