UBR3

Across TCGA cell cohorts, UBR3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,092 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UBR3-associated GO terms across cancer lineages are Peptidyl-serine modification, Peptidyl-serine phosphorylation, and Late viral transcription. Each is linked with UBR3 in more than 16 cancer types. Because this analysis shows association rather than direction, both UBR3-to-partner and partner-to-UBR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-serine modification grouped by UBR3-low versus UBR3-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBR3→partner) and Y-score (partner→UBR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Peptidyl-serine modification →	+0.078	+0.611	<.001	.002	2	17
BREAST	Peptidyl-serine phosphorylation →	+0.069	+0.691	.001	<.001	2	16
LARGE_INTESTINE	Late viral transcription →	+0.114	+0.628	<.001	.001	3	15
LUNG_SCLC	Negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel →	+0.203	+0.646	.009	<.001	3	14
STOMACH	Regulation of endoplasmic reticulum tubular network organization →	+0.124	+0.737	.003	.002	3	14
BLOOD_Leukemia	Ubiquitin-dependent protein catabolic process via the N-end rule pathway →	+0.098	+0.792	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,092 associations by consensus.

Peptidyl-serine modification by UBR3 expression — OVARY

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