UBQLN4

Across TCGA patient cohorts, UBQLN4 mutation is significantly associated with the RNA expression of many other genes, with 1,277 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBQLN4-associated genes across cancer lineages are RN7SL248P, LINC02709, and STX18-AS1. Each is linked with UBQLN4 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBQLN4-to-partner and partner-to-UBQLN4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by UBQLN4-low versus UBQLN4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBQLN4→partner) and Y-score (partner→UBQLN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.059	+3.137	<.001	.005	3	2
SKCM	LINC02709 →	+0.416	+3.353	.004	.005	3	2
SKCM	STX18-AS1 →	+0.403	+3.366	<.001	.005	3	2
COAD	RNU6ATAC30P →	+1.483	+5.893	<.001	.002	3	2
COAD	LINC01491 →	+0.189	+6.392	<.001	.001	3	2
UCEC	PIP4K2A →	+0.604	+3.708	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,277 associations by consensus.

RN7SL248P by UBQLN4 expression — UCEC

Explore this box plot interactively →