STX18 antisense RNA 1 (head to head)Genealiases: []
Q-omics provides the consensus-scored STX18-AS1 profile across patient tissues and cancer cell-line models. STX18-AS1 expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in UCS. Among the 18 cancer types available for tumor–normal comparison, STX18-AS1 is differentially expressed in 10, with the highest sampling consensus in KIRC. Additionally, STX18-AS1 RNA expression shows 20,900 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight UCS, KIRC, and ACC as cancer lineages where STX18-AS1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for STX18-AS1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes STX18-AS1 survival associations across molecular data types. STX18-AS1 RNA expression shows survival associations in the most cancer types (22). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible STX18-AS1 RNA expression–survival associations across cancer types. High STX18-AS1 expression shows unfavorable associations in THCA, KIRP and ACC, but favorable associations in UCS, READ and PAAD. The UCS Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .001). Together, the overview and detailed table identify UCS as the clearest survival context for STX18-AS1 RNA expression.
This table summarizes STX18-AS1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for STX18-AS1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. STX18-AS1 shows lower tumor expression in KIRC and THCA and higher tumor expression in COAD, LIHC, STAD and CHOL. The KIRC box plot shows higher STX18-AS1 RNA expression in normal versus tumor tissue (log2 FC = −0.469, t-test p < 0.001).
This table shows molecular features associated with STX18-AS1 in patient tissues and cancer cell lines. In patient samples, STX18-AS1 shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set.
