Across TCGA cell cohorts, UBQLN3 RNA expression is significantly associated with the mutation status of many other genes, with 85 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible UBQLN3-associated genes across cancer lineages are PTGFRN, REV3L, and SPHKAP. Each is linked with UBQLN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBQLN3-to-partner and partner-to-UBQLN3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBQLN3→partner) and Y-score (partner→UBQLN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	PTGFRN →	+5.754	+0.006	.002	<.001	3	2
SKIN	REV3L →	+3.415	+0.006	.001	<.001	3	2
BLOOD_Leukemia	SPHKAP →	+2.644	+0.026	.008	<.001	3	2
BLOOD_Leukemia	ACTR3B →	+4.551	+0.029	.004	<.001	3	2
SOFT_TISSUE	CHD6 →	+4.977	+0.020	.002	<.001	3	1
SOFT_TISSUE	LDLR →	+4.977	+0.020	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 85 associations by consensus.

Exploration

UBQLN3 survival (RNA) · tumor vs normal (RNA) · all UBQLN3 data types