UBN1

Across TCGA patient cohorts, UBN1 mutation is significantly associated with the RNA expression of many other genes, with 3,253 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBN1-associated genes across cancer lineages are GPR143, MT1XP1, and NSA2P7. Each is linked with UBN1 in more than 2 cancer types. Because this analysis shows association rather than direction, both UBN1-to-partner and partner-to-UBN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GPR143 grouped by UBN1-low versus UBN1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBN1→partner) and Y-score (partner→UBN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GPR143 →	-0.454	-1.404	.007	.002	3	3
UCEC	MT1XP1 →	+0.461	+1.758	.002	.003	3	3
UCEC	NSA2P7 →	+0.383	+1.801	<.001	.001	3	3
BRCA	RNA5SP468 →	+0.356	+4.250	<.001	.003	3	2
UCEC	LINC02538 →	-0.083	-1.744	.003	<.001	3	2
SKCM	RPEP5 →	+0.026	+3.980	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,253 associations by consensus.

GPR143 by UBN1 expression — UCEC

Explore this box plot interactively →