UBL4A

Across TCGA patient cohorts, UBL4A mutation is significantly associated with the RNA expression of many other genes, with 1,626 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBL4A-associated genes across cancer lineages are MIR550A1, MIR16-1, and NFYAP1. Each is linked with UBL4A in more than 1 cancer types. Because this analysis shows association rather than direction, both UBL4A-to-partner and partner-to-UBL4A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR550A1 grouped by UBL4A-low versus UBL4A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBL4A→partner) and Y-score (partner→UBL4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR550A1 →	+0.361	+2.462	<.001	.004	3	2
UCEC	MIR16-1 →	+0.240	+3.928	<.001	.007	3	2
CESC	NFYAP1 →	+0.246	+5.010	<.001	.009	3	1
CESC	RPL31P59 →	+0.133	+5.010	<.001	.009	3	1
CESC	CYCTP →	+0.260	+5.306	.003	.006	3	1
CESC	RANP9 →	+0.191	+6.837	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,626 associations by consensus.

MIR550A1 by UBL4A expression — UCEC

Explore this box plot interactively →