UBL4A

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, UBL4A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,223 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible UBL4A-associated GO terms across cancer lineages are snRNA pseudouridine synthesis, Positive regulation of telomerase RNA localization to Cajal body, and Positive regulation of cell cycle checkpoint. Each is linked with UBL4A in more than 13 cancer types. Because this analysis shows association rather than direction, both UBL4A-to-partner and partner-to-UBL4A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, snRNA pseudouridine synthesis grouped by UBL4A-low versus UBL4A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBL4A→partner) and Y-score (partner→UBL4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONEsnRNA pseudouridine synthesis →+0.110+0.870<.001<.001314
UPPER_AERODIGESTIVE_TRACTPositive regulation of telomerase RNA localization to Cajal body →+0.136+0.860<.001.001313
OESOPHAGUSPositive regulation of cell cycle checkpoint →+0.148+0.788.001.007311
PANCREASSpindle elongation →+0.219+0.791<.001<.001311
UPPER_AERODIGESTIVE_TRACTDNA replication-dependent chromatin assembly →+0.146+0.815<.001<.001311
PANCREASMitotic spindle elongation →+0.277+1.085<.001<.001311
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,223 associations by consensus.

snRNA pseudouridine synthesis by UBL4A expression — BONE

Box plot of snRNA pseudouridine synthesis in UBL4A-low vs UBL4A-high samples in BONE.

Explore this box plot interactively →

Exploration