UBE2S

Across TCGA patient cohorts, UBE2S mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBE2S-associated genes across cancer lineages are CD4+ Tcm and CD8+ Tem. Each is linked with UBE2S in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2S-to-partner and partner-to-UBE2S results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ Tcm grouped by UBE2S-low versus UBE2S-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2S→partner) and Y-score (partner→UBE2S) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	CD4+ Tcm →	+0.080	+4.527	<.001	.017	3	1
UCEC	CD8+ Tem →	+0.005	+5.258	<.001	.029	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CD4+ Tcm by UBE2S expression — BLCA

Explore this box plot interactively →