UBE2K

Across TCGA patient cohorts, UBE2K protein abundance is significantly associated with the RNA expression of many other genes, with 7,290 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible UBE2K-associated genes across cancer lineages are GRPEL1, UGDH, and SLBP. Each is linked with UBE2K in more than 5 cancer types. Because this analysis shows association rather than direction, both UBE2K-to-partner and partner-to-UBE2K results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBE2K versus GRPEL1 in UCEC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2K→partner) and Y-score (partner→UBE2K) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GRPEL1 →	+0.725	+0.215	.005	<.001	3	6
BRCA	UGDH →	+0.815	+0.212	<.001	<.001	3	5
UCEC	SLBP →	+0.701	+0.241	.001	<.001	3	5
BRCA	MRFAP1 →	+0.453	+0.251	<.001	<.001	3	5
UCEC	NCAPG →	+1.026	+0.200	<.001	<.001	3	5
OV	SLC30A9 →	+0.590	+0.259	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,290 associations by consensus.

UBE2K vs GRPEL1 — UCEC

Explore this scatter interactively →