UBE2I

Across TCGA patient cohorts, UBE2I protein abundance is significantly associated with the RNA expression of many other genes, with 426 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible UBE2I-associated genes across cancer lineages are ASPHD1, BTF3P7, and CRHR2. Each is linked with UBE2I in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2I-to-partner and partner-to-UBE2I results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBE2I versus ASPHD1 in LUAD, with a Pearson correlation of 0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2I→partner) and Y-score (partner→UBE2I) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ASPHD1 →	+2.575	+0.443	.003	.001	3	2
LUAD	BTF3P7 →	+1.122	+0.443	.001	.001	3	2
LUAD	CRHR2 →	+0.736	+0.536	.001	.007	3	1
LUAD	DHX40 →	+0.403	+0.443	.007	.001	3	1
LUAD	DPPA4 →	+0.048	+0.443	.002	.001	3	1
LUAD	SLC25A16 →	+0.799	+0.536	.003	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 426 associations by consensus.

UBE2I vs ASPHD1 — LUAD

Explore this scatter interactively →