UBE2I

Across TCGA patient cohorts, UBE2I mutation is significantly associated with the RNA expression of many other genes, with 1,725 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBE2I-associated genes across cancer lineages are RNU1-17P, RPS29P32, and RNU6ATAC25P. Each is linked with UBE2I in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2I-to-partner and partner-to-UBE2I results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-17P grouped by UBE2I-low versus UBE2I-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2I→partner) and Y-score (partner→UBE2I) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU1-17P →	+0.202	+2.557	<.001	.003	3	2
UCEC	RPS29P32 →	+0.459	+2.221	<.001	.008	3	2
COAD	RNU6ATAC25P →	+0.570	+5.332	<.001	.002	3	2
COAD	RNU2-48P →	+0.946	+4.807	<.001	.004	3	2
CESC	TAS2R7 →	+0.038	+5.144	<.001	.003	3	1
CESC	KRTAP4-3 →	+0.122	+6.584	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,725 associations by consensus.

RNU1-17P by UBE2I expression — UCEC

Explore this box plot interactively →