UBE2I

Across TCGA cell cohorts, UBE2I protein abundance is significantly associated with the RNA expression of many other genes, with 4,814 significant associations in total. BONE shows the largest number of these associations.

The most reproducible UBE2I-associated genes across cancer lineages are LUC7L, METTL21A, and TBC1D24. Each is linked with UBE2I in more than 8 cancer types. Because this analysis shows association rather than direction, both UBE2I-to-partner and partner-to-UBE2I results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBE2I versus LUC7L in BONE, with a Pearson correlation of 0.86.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2I→partner) and Y-score (partner→UBE2I) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	LUC7L →	+0.934	+1.548	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	METTL21A →	+1.035	+1.077	<.001	<.001	3	8
LUNG_SCLC	TBC1D24 →	+1.323	+1.477	<.001	<.001	3	7
LUNG_SCLC	RNPS1 →	+0.639	+1.205	<.001	<.001	3	7
LIVER	RPS15A →	+0.813	+0.900	.002	.002	3	7
LUNG_SCLC	MLST8 →	+0.436	+0.663	.008	.005	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,814 associations by consensus.

UBE2I vs LUC7L — BONE

Explore this scatter interactively →