Across TCGA patient cohorts, UBE2F mutation is significantly associated with the RNA expression of many other genes, with 216 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBE2F-associated genes across cancer lineages are CHEK2P5, MTCO3P46, and UBL5P3. Each is linked with UBE2F in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2F-to-partner and partner-to-UBE2F results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2F→partner) and Y-score (partner→UBE2F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CHEK2P5 →	+0.440	+6.003	<.001	.002	3	2
COAD	MTCO3P46 →	+0.607	+5.602	<.001	.004	3	2
COAD	UBL5P3 →	+0.627	+5.893	<.001	.002	3	2
COAD	PSMB7P1 →	+0.236	+5.790	<.001	.003	3	2
UCEC	RNU4-76P →	+0.277	+4.137	<.001	<.001	3	2
COAD	ATP5PBP2 →	+0.354	+5.017	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 216 associations by consensus.

Exploration

UBE2F survival (RNA) · tumor vs normal (RNA) · all UBE2F data types