CHEK2P5

Q-omics provides the consensus-scored CHEK2P5 profile across patient tissues and cancer cell-line models. CHEK2P5 expression is associated with patient survival in 6 of 34 cancer types, with the highest sampling consensus in KIRC. Additionally, CHEK2P5 RNA expression shows 6,136 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight KIRC, and STAD as cancer lineages where CHEK2P5 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes CHEK2P5 survival associations across molecular data types. CHEK2P5 RNA expression shows survival associations in the most cancer types (6). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

CHEK2P5 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	6	KIRC (60)	view →

This table ranks reproducible CHEK2P5 RNA expression–survival associations across cancer types. High CHEK2P5 expression shows unfavorable associations in THCA, KICH, COAD and STAD, but favorable associations in KIRC and OV. The KIRC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .007). Together, the overview and detailed table identify KIRC as the clearest survival context for CHEK2P5 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	II,III,IV	0.889	0.510	.007	60	view →
THCA	OS	Tertile	III,IV	0.564	0.964	<.001	45	view →
KICH	DFS	Tertile	All	0.673	0.934	.027	18	view →
COAD	DFS	Tertile	III,IV	0.200	0.567	.008	18	view →
OV	DFS	Tertile	IV	1.000	0.244	.042	12	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →

Pink = unfavorable, green = favorable. all 6 lineages →

CHEK2P5-KIRC (DFS)

Explore this curve interactively →