UBB

Across TCGA patient cohorts, UBB mutation is significantly associated with the RNA expression of many other genes, with 882 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBB-associated genes across cancer lineages are SNRPGP7, RNU6-1101P, and SNORD114-15. Each is linked with UBB in more than 1 cancer types. Because this analysis shows association rather than direction, both UBB-to-partner and partner-to-UBB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNRPGP7 grouped by UBB-low versus UBB-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBB→partner) and Y-score (partner→UBB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SNRPGP7 →	+0.613	+5.602	<.001	.004	3	2
UCEC	RNU6-1101P →	+0.538	+2.813	<.001	.005	3	2
LUSC	SNORD114-15 →	+0.464	+7.924	<.001	.008	3	2
UCEC	RNA5SP414 →	+0.821	+2.577	<.001	.004	3	1
UCEC	MIR1273H →	+0.317	+3.451	<.001	<.001	3	1
UCEC	C17orf98 →	+0.472	+3.713	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 882 associations by consensus.

SNRPGP7 by UBB expression — COAD

Explore this box plot interactively →