UBASH3B

Across TCGA cell cohorts, UBASH3B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,953 significant associations in total. BONE shows the largest number of these associations.

The most reproducible UBASH3B-associated GO terms across cancer lineages are Positive regulation of focal adhesion assembly, Protein depolymerization, and Positive regulation of cytoskeleton organization. Each is linked with UBASH3B in more than 13 cancer types. Because this analysis shows association rather than direction, both UBASH3B-to-partner and partner-to-UBASH3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of focal adhesion assembly grouped by UBASH3B-low versus UBASH3B-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBASH3B→partner) and Y-score (partner→UBASH3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of focal adhesion assembly →	+0.225	+2.764	<.001	<.001	3	14
OVARY	Protein depolymerization →	+0.109	+1.788	<.001	<.001	3	13
BONE	Positive regulation of cytoskeleton organization →	+0.069	+2.153	<.001	<.001	3	13
BONE	Positive regulation of cell-substrate junction organization →	+0.167	+1.846	<.001	<.001	3	13
LIVER	Actin filament depolymerization →	+0.213	+2.726	<.001	.002	3	13
BONE	Negative regulation of Rho protein signal transduction →	+0.239	+2.571	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,953 associations by consensus.

Positive regulation of focal adhesion assembly by UBASH3B expression — BONE

Explore this box plot interactively →