UBASH3B

Across TCGA cell cohorts, UBASH3B mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UBASH3B-associated genes across cancer lineages are C1orf87, CLEC4G, and CD300LD. Each is linked with UBASH3B in more than 1 cancer types. Because this analysis shows association rather than direction, both UBASH3B-to-partner and partner-to-UBASH3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C1orf87 grouped by UBASH3B-low versus UBASH3B-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBASH3B→partner) and Y-score (partner→UBASH3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	C1orf87 →	+0.033	+4.906	<.001	.006	3	1
OESOPHAGUS	CLEC4G →	+0.013	+4.906	<.001	.006	3	1
OESOPHAGUS	CD300LD →	+0.013	+4.906	<.001	.006	3	1
LARGE_INTESTINE	TECRL →	+0.011	+3.240	<.001	.004	3	1
LARGE_INTESTINE	FCGR2B →	+0.114	+2.716	.002	.009	3	1
BLOOD_Lymphoma	KRT9 →	+0.050	+4.191	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

C1orf87 by UBASH3B expression — OESOPHAGUS

Explore this box plot interactively →