UBASH3A

Across TCGA patient cohorts, UBASH3A protein abundance is significantly associated with the RNA expression of many other genes, with 6,853 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible UBASH3A-associated genes across cancer lineages are PYHIN1, CD48, and LY9. Each is linked with UBASH3A in more than 4 cancer types. Because this analysis shows association rather than direction, both UBASH3A-to-partner and partner-to-UBASH3A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBASH3A versus PYHIN1 in PDAC, with a Pearson correlation of 0.98.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBASH3A→partner) and Y-score (partner→UBASH3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PYHIN1 →	+1.556	+1.280	.004	.008	3	5
HNSC	CD48 →	+1.652	+0.727	<.001	.006	3	4
LSCC	LY9 →	+1.165	+0.576	<.001	<.001	3	4
HNSC	TRAT1 →	+1.554	+0.697	<.001	.006	3	4
HNSC	CXCR6 →	+1.752	+0.822	.005	.004	3	4
PDAC	THEMIS →	+1.803	+1.280	.004	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,853 associations by consensus.

UBASH3A vs PYHIN1 — PDAC

Explore this scatter interactively →