UBAP2L

Across TCGA patient cohorts, UBAP2L mutation is significantly associated with the total protein of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBAP2L-associated genes across cancer lineages are EGFR_pY1068, FoxM1, and Acetyl-a-Tubulin-Lys40. Each is linked with UBAP2L in more than 1 cancer types. Because this analysis shows association rather than direction, both UBAP2L-to-partner and partner-to-UBAP2L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1068 grouped by UBAP2L-low versus UBAP2L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBAP2L→partner) and Y-score (partner→UBAP2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.276	-1.925	.002	.005	3	2
UCEC	FoxM1 →	+0.212	+1.925	.022	.005	3	2
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.543	+1.916	.002	.009	3	2
UCEC	p38-MAPK_pT180_Y182 →	-0.447	-1.912	.005	.005	3	2
UCEC	PCNA →	+0.243	+3.700	.001	.001	3	2
UCEC	Src_pY416 →	-0.252	-2.906	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

EGFR_pY1068 by UBAP2L expression — UCEC

Explore this box plot interactively →