UBAP2L

Across TCGA pan-cancer cohorts, UBAP2L RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of UBAP2L’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where UBAP2L RNA is more highly expressed in tumor relative to normal tissue. In most cancer types UBAP2L is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

HNSC, COAD, and KIRP are the cancer types where UBAP2L tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in UBAP2L RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	All	+0.983	<.001	12	view →
COAD	Male	IV	+1.286	<.001	11	view →
KIRP	All	III,IV	+0.776	<.001	10	view →
LIHC	Female	II,III,IV	+1.750	<.001	9	view →
BLCA	Female	III,IV	+0.791	<.001	9	view →
LUAD	All	III,IV	+0.663	<.001	9	view →
STAD	Male	II,III,IV	+0.978	<.001	8	view →
LUSC	Female	All	+0.882	<.001	8	view →
BRCA	All	III,IV	+0.897	<.001	6	view →
UCEC	All	All	+0.571	<.001	6	view →
CHOL	Male	All	+2.923	<.001	5	view →
READ	All	All	+0.843	<.001	5	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

UBAP2L–HNSC

Open the HNSC breakdown →