UBAP2L

Across TCGA pan-cancer cohorts, UBAP2L RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated UBAP2L data layer compared with 5 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in small cell lung cancer (SCLC), where higher UBAP2L RNA is associated with better overall survival. In most high-consensus cancer types, elevated UBAP2L expression acts as an unfavorable survival marker, although some lineages such as SCLC and PAAD show a favorable association.

SCLC, ACC, and KIRP are the cancer types where UBAP2L RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	OS	Median	III,IV	0.812	0.432	<.001	96	view →
ACC	DFS	Median	All	0.400	0.758	<.001	91	view →
KIRP	DFS	Tertile	All	0.757	0.931	<.001	85	view →
LIHC	OS	Median	All	0.709	0.839	<.001	65	view →
SKCM	OS	Median	III,IV	0.619	0.792	<.001	45	view →
KICH	DFS	Quartile	All	0.461	0.900	.004	35	view →
ESCA	DFS	Median	III,IV	0.275	0.577	<.001	30	view →
LUSC	DFS	Quartile	III,IV	0.313	0.897	.008	27	view →
STAD	OS	Tertile	II,III,IV	0.626	0.755	.022	16	view →
PAAD	OS	Tertile	II,III,IV	0.516	0.281	.003	16	view →
GBM	DFS	Median	All	0.388	0.188	.001	15	view →
BLCA	DFS	Median	All	0.159	0.488	.002	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

UBAP2L–SCLC (OS)

Open the SCLC breakdown →