UBAP2L

Across TCGA cell cohorts, UBAP2L mutation is significantly associated with the RNA expression of many other genes, with 241 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UBAP2L-associated genes across cancer lineages are PRAMEF27, CST11, and SIGLEC16. Each is linked with UBAP2L in more than 1 cancer types. Because this analysis shows association rather than direction, both UBAP2L-to-partner and partner-to-UBAP2L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRAMEF27 grouped by UBAP2L-low versus UBAP2L-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBAP2L→partner) and Y-score (partner→UBAP2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PRAMEF27 →	+0.019	+4.969	<.001	.003	3	2
BLOOD_Lymphoma	CST11 →	+0.561	+2.807	<.001	.004	3	1
BLOOD_Lymphoma	SIGLEC16 →	+0.149	+3.371	<.001	.008	3	1
BLOOD_Lymphoma	SLC38A8 →	+0.060	+2.928	<.001	.002	3	1
BLOOD_Lymphoma	CST9 →	+0.040	+3.209	<.001	.004	3	1
BLOOD_Lymphoma	CYLC1 →	+0.010	+2.867	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 241 associations by consensus.

PRAMEF27 by UBAP2L expression — BLOOD_Leukemia

Explore this box plot interactively →