UBA6

Across TCGA patient cohorts, UBA6 protein abundance is significantly associated with the RNA expression of many other genes, with 11,377 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible UBA6-associated genes across cancer lineages are UBA6-AS1, C1orf115, and RAMP2-AS1. Each is linked with UBA6 in more than 5 cancer types. Because this analysis shows association rather than direction, both UBA6-to-partner and partner-to-UBA6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBA6 versus UBA6-AS1 in HNSC, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBA6→partner) and Y-score (partner→UBA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	UBA6-AS1 →	+0.394	+0.301	<.001	<.001	3	6
CCRCC	C1orf115 →	-1.039	-0.363	<.001	<.001	3	5
BRCA	RAMP2-AS1 →	-1.250	-0.322	<.001	<.001	3	5
OV	GRSF1 →	+0.402	+0.225	<.001	.003	3	5
OV	UTP3 →	+0.545	+0.390	<.001	<.001	3	5
PDAC	USO1 →	+0.467	+0.306	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,377 associations by consensus.

UBA6 vs UBA6-AS1 — HNSC

Explore this scatter interactively →