UAP1L1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, UAP1L1 mutation is significantly associated with the RNA expression of many other genes, with 127 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UAP1L1-associated genes across cancer lineages are ELOCP4, MTND5P3, and IGHD1-26. Each is linked with UAP1L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both UAP1L1-to-partner and partner-to-UAP1L1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UAP1L1→partner) and Y-score (partner→UAP1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAELOCP4 →+0.074+8.471<.001.00532
COADMTND5P3 →+0.137+3.636<.001.00632
UCECIGHD1-26 →+0.895+3.484<.001.00432
UCECMIR1229 →+0.201+4.069<.001.00832
UCECRNA5SP146 →+0.396+3.203<.001.00332
UCECRNA5SP436 →+0.312+3.937.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 127 associations by consensus.

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