Q-omics provides the consensus-scored MTND5P3 profile across patient tissues and cancer cell-line models. MTND5P3 expression is associated with patient survival in 9 of 34 cancer types, with the highest sampling consensus in SKCM. Among the 18 cancer types available for tumor–normal comparison, MTND5P3 is differentially expressed in 2, with the highest sampling consensus in THCA. Additionally, MTND5P3 RNA expression shows 5,264 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight SKCM, THCA, and STAD as cancer lineages where MTND5P3 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MTND5P3 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MTND5P3 survival associations across molecular data types. MTND5P3 RNA expression shows survival associations in the most cancer types (9). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MTND5P3 RNA expression–survival associations across cancer types. High MTND5P3 expression shows unfavorable associations in SKCM, READ, THYM, THCA, LUSC and ACC. The SKCM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .002). Together, the overview and detailed table identify SKCM as the clearest survival context for MTND5P3 RNA expression.
This table summarizes MTND5P3 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for MTND5P3. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MTND5P3 shows lower tumor expression in THCA and ESCA. The THCA box plot shows higher MTND5P3 RNA expression in normal versus tumor tissue (log2 FC = −0.007, t-test p = .018).
This table shows molecular features associated with MTND5P3 in patient tissues and cancer cell lines. In patient samples, MTND5P3 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
