MTND5P3

Across TCGA pan-cancer cohorts, MTND5P3 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MTND5P3’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where MTND5P3 RNA is repressed in tumor relative to normal tissue. In most cancer types MTND5P3 is over-expressed in tumor, although a few such as THCA and ESCA show the opposite, repressed pattern.

THCA and ESCA are the cancer types where MTND5P3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MTND5P3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	II,III,IV	−0.007	.018	2	view →
ESCA	All	All	−0.050	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

MTND5P3–THCA

Open the THCA breakdown →